West Ham United entertain Manchester United at the London Stadium on Sunday afternoon.
And West Ham boss David Moyes has a few decisions to make regarding his team selection as he looks to cope without two key stars.
Moyes welcomes his old club to the London Stadium with both West Ham and Man United unbeaten in the Premier League so far.
Man United warmed up for the trip to east London with a 2-1 loss in the Champions League in midweek.
West Ham meanwhile produced a perfect, professional performance to beat Croatian champions Dinamo Zagreb 2-0 in their own back yard in the Europa League on Thursday night.
The Hammers were already missing key man Michail Antonio for the Man United game after his sending off against Southampton last weekend.
And Moyes revealed in his pre-match press briefing that Said Benrahma has picked up a knock and could miss the match too.
As a result Moyes looks set to make three changes to the side which beat Zagreb on Thursday night.
Many believed the pair would share number on duties. But it appears Moyes sees the goalkeeping situation as a straight shootout between Fabianski and Areola for the number one spot.
And that means Moyes will stick with Fabianski for the time being at least.
The first change comes at right-back with Vladimir Coufal coming back into the side in place of the excellent Ryan Fredericks.
Coufal was rested against Zagreb and Fredericks did his chances no harm at all with a superb performance.
But Coufal will come back in with Fredericks likely to face Man United in the Carabao Cup game on Wednesday night.
New boy Kurt Zouma showed his class in Zagreb. And he will surely keep his place while Angelo Ogbonna comes back in for Issa Diop in the second change.
With Antonio suspended, Nikola Vlasic looks set to start as a false nine.
Behind him Manuel Lanzini will start again after being substituted early in the second half in Croatia given he was walking a red card tight rope.
That means Pablo Fornals will play out on the left while Jarrod Bowen comes back in as third change on the right.
It is such a shame West Ham are missing Premier League player of the month Antonio for such a big game.
There may be a glimmer of hope that Benrahma could still make it and if he does start it will be in place of Lanzini.
Predicted West Ham starting XI to face Man United without Benrahma:
Fabianski, Coufal, Zouma, Ogbonna, Cresswell, Soucek, Rice, Fornals, Lanzini, Bowen, Vlasic.
Predicted West Ham starting XI to face Man United with Benrahma:
Fabianski, Coufal, Zouma, Ogbonna, Cresswell, Soucek, Rice, Fornals, Benrahma, Bowen, Vlasic.